An experimental model for cystometric evaluation in unanesthetized rats

ABSTRACT

PE 50 catheters were implanted in the bladder of Wistar rats. which would permit urodynamic evaluation without use of general anesthesia. After cystostomy, the rats were placed in "retaining"cages for cystometric and flowmetric readings. Experimental observation was initiated more than two hours after surgery. With continuous infusion of liquid in the bladder through cystotomy, at a flow of 0.3 ml/min, the rats presented average micturition pressure of 33.36 mmHg (SD + 10.08)an average maximum vesical capacity of 0.29 ml (SD + 0.1) and a micturition at intervals of 56.3 s (SD + 10.9).