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Acute effects on bone marrow after association between Radiosensitizer and X rays-NN/N method
Interciencia ; 19(2): 75-8, mar.-abr. 1994. ilus
Article in English | LILACS | ID: lil-163405
RESUMO
A histopathological and morphometric study was performed in the bone marrow of mice after association of cisdiamminedi-choroplatinum II (3.0 mg/kg) plus X-rays (103.20 mC/Kg 400R). Rstimation of bone marrow effects was assessed by counting the number of non nucleated-erythrocytes (NN) and nucleated (N) cells, and establishing (NN/N) ratio. The morphomeric method used correlates and makes possible quantification of histopathologic changes of bone marrow through relation of vascular stroma and cellular parenchyma. It can be used as a biological dosimetry parameter and to estimate injury and recovery of hematologic evolution of different myelotoxic agents
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Index: LILACS (Americas) Main subject: Radiometry / Ions Type of study: Risk factors Language: English Journal: Interciencia Journal subject: Medicine Year: 1994 Type: Article

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Index: LILACS (Americas) Main subject: Radiometry / Ions Type of study: Risk factors Language: English Journal: Interciencia Journal subject: Medicine Year: 1994 Type: Article