Allergic skin rash with lamotrigine and concomitant valproate therapy
Arq. neuropsiquiatr
;
54(1): 47-9, mar. 1996. tab
Article
in English
| LILACS
| ID: lil-164053
ABSTRACT
Cutaneous rash is one of the commonest adverse events associated with lamotrigine. We assessed whether the risk is increased in patients receiving concomitant valproate therapy in a population of 103 adult patients with intractable epilepsy, who had lamotrigine added to their treatment. Of the 33 patients taking valproate, 10 (30 per cent) developed a rash, whilst of the 70 not taking valproate, only 6 (8 per cent) developed a rash. This suggests a significantly higher risk of cutaneous rash when starting lamotrigine in patients already taking valproate (p
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Drug Eruptions
/
Anticonvulsants
Limits:
Adolescent
/
Adult
/
Female
/
Humans
/
Male
Language:
English
Journal:
Arq. neuropsiquiatr
Journal subject:
Neurology
/
Psychiatry
Year:
1996
Type:
Article
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Full text:
Available
Index:
LILACS (Americas)
Main subject:
Drug Eruptions
/
Anticonvulsants
Limits:
Adolescent
/
Adult
/
Female
/
Humans
/
Male
Language:
English
Journal:
Arq. neuropsiquiatr
Journal subject:
Neurology
/
Psychiatry
Year:
1996
Type:
Article