Plummer-Vinson (Paterson-Kelly) syndrome and iron repletion therapy: a case report / Síndrome de Plummer-Vinson (Paterson-Kelly) e tratamento po reposiçåo de ferro: comunicaçåo de caso

ABSTRACT

Plummer-Vinson or Paterson-Kelly syndrome is characterized by cervical dysphagia secondary to benign upper esophageal stricture associated with iron deficiency anemia and glossitis. A 26 years old female with a one-year history of severe progressive cervical dysphagia is presented. The patient had glossitis, angular cheilitis, dry skin and total loss of teeth. Hematocrit was 24 percent, hemoglobin 7 d/dl, and mean corpuscular volume (MCV) 85.7 fL. Barium esophagrams showed a 65 percent stricture at C5-C6 level. After iron repletion therapy with ferrous sulfate 300 mcg TID-BID for 25 months the patient was assymptomatic. Hematocrit was 38 percent, hemoglobin 12.8 g/dl, MCV 88.4 fL Esophageal stricture seemed reduced to 40 percent