Regulation of G0 G1 S transition: a genetic approach
Ciênc. cult. (Säo Paulo)
;
46(1/2): 86-7, Jan.-Abr. 1994. tab
Article
in English
| LILACS
| ID: lil-172016
ABSTRACT
A genetic approach was adopted to analyze the cell cycle G(O)(G (1) (S transition in mouse Balb/ 3T3 fibroblasts (clone A3l). We designed selection procedures to isolate revertant from the EJ-ras transformed Balb/3T3 ribroblasts that had recovered strict -control of the G(O) ( G(1), transition by serum growth factors. The aim was to uncover phenotypic traits associated with malignancy (high growth rate G(1) phase shortening and high tumorigenicity) that segregate independently.
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Index:
LILACS (Americas)
Main subject:
Cell Division
/
Gene Expression Regulation
/
Resting Phase, Cell Cycle
/
G1 Phase
/
S Phase
/
Growth Substances
/
Clone Cells
Limits:
Animals
Language:
English
Journal:
Ciênc. cult. (Säo Paulo)
Journal subject:
Science
Year:
1994
Type:
Article
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