Cuadro inicial del síndrome nefrósico primario del niño: evaluación a 18 meses de dos esquemas de tratamiento con prednisona / Initial status of primary nephrotic syndrome in children: assessment at 18 months of 2 treatment schemes with prednisone
Rev. méd. Chile
;
124(5): 567-72, mayo 1996. tab, graf
Article
in Spanish
| LILACS
| ID: lil-174775
RESUMO
Ninety six patients agred from 6 months to 16 years old were admitted to chilean hospitals with the diagnosis of primary nephrotic syndrome in a period of 30 months. These patients were randomly separated in 2 groups, group A received prednosone for 8 weeks and group B received the same drug during 12 weeks. All patients were evaluated at 6, 12 and 18 months after the end of treatment. The moment and number of relapses per patient, accumulated percentage of relapses, relapse rate per 100 patients, total number of relapses and complications were assessed. Frequent relapsers were subjected to a kidney biopsy, leaving in the protocol only those patients that had minimal changes. Patients resistent or dependant to steroid therapy were discarded. Thus we report the results of 56 treated poatients followed during 18 months. No differences in analyzed parameters were observed between the 2 treatment groups. It is concluded that these preliminary results do not support the prolongation of prednisone treatment in children with primary nephrotic syndrome
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Index:
LILACS (Americas)
Main subject:
Prednisone
/
Nephrotic Syndrome
Type of study:
Practice guideline
/
Observational study
/
Prognostic study
Limits:
Adolescent
/
Child, preschool
/
Female
/
Humans
/
Infant
/
Male
Language:
Spanish
Journal:
Rev. méd. Chile
Journal subject:
Medicine
Year:
1996
Type:
Article
/
Project document
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