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The incidence of lethal graft-versus-host disease in rat limb allotransplantations
Ferreira, L. M; Borsanyi, J. P; Benhaim, P; Anthony, J. P; Mathes, S. J; Andrews, J. M; Laredo Filho, J.
Rev. Hosp. Säo Paulo Esc. Paul. Med ; 6(1/2): 7-10, Jan.-Jun. 1995. ilus
Article in English | LILACS | ID: lil-179684
ABSTRACT
To study graft-versus-host disease (GVHD) in rat hindlimb allotransplantation, a model similar to intestinal transplantation was used. ACI and Lewis rats were crossed to produce F(1) generation rats (ACI-Lewis). These underwent limb transplantation receiving a donor limb from a Lewis rat. The animals were examined daily and skin biopsies were performed. Results showed that all limbs were viable at 34 weeks and no rats demonstrated any clinical evidence of GVHD and biopsies were grade 0.
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Index: LILACS (Americas) Main subject: Extremities / Graft vs Host Disease Type of study: Incidence study / Prognostic study / Risk factors Limits: Animals Language: English Journal: Rev. Hosp. Säo Paulo Esc. Paul. Med Journal subject: Medicine Year: 1995 Type: Article

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Index: LILACS (Americas) Main subject: Extremities / Graft vs Host Disease Type of study: Incidence study / Prognostic study / Risk factors Limits: Animals Language: English Journal: Rev. Hosp. Säo Paulo Esc. Paul. Med Journal subject: Medicine Year: 1995 Type: Article