The role of apoptosis in the inhibition of a secondary tumor by concomitant resistance in a mouse model of metastases
Medicina (B.Aires)
;
56(4): 393-6, 1996. ilus, tab
Article
in English
| LILACS
| ID: lil-186262
ABSTRACT
Resistance of tumor-bearing mice to a second tumor challenge, that is, concomitant resistance, was studied using the LB tumor model. In a secondary LB tumor implant inhibited by concomitant resistance an increase in the percentage of apoptotic cells and alterations in cell cycle distribution were observed. Similar alterations were observed in LB tumor cells incubated with serum from tumor-bearing mice. The data presented in this paper suggest that apoptosis is one of the mechanisms involved in tumor dormancy due to concomitant resistance.
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Index:
LILACS (Americas)
Main subject:
Apoptosis
/
Lymphoma
/
Neoplasm Metastasis
Limits:
Animals
Language:
English
Journal:
Medicina (B.Aires)
Journal subject:
Medicine
Year:
1996
Type:
Article
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