Htlv-I infection and adult T-cell leukemia in Brazil: an overview
São Paulo med. j
; 114(3): 1177-85, maio-jun. 1996. mapas, tab
Article
in En
| LILACS
| ID: lil-186683
Responsible library:
BR1.1
RESUMO
Human T-cell lymphotropic Virus Type I (HTLV-1) is the etiologic factor for adult T-cell leukemia/lymphoma (ATL). HTLV-1 infection can aiso lead to other diseases, such as HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP), uveitis, arthropathy and infectious dermatitis. Studies of the infectious mode of transmission of HTLV-1 and risk factors for HTLV-l-related diseases have been conducted in several countries, and differences in the prevalence, age patterns, ethnic groups and clinical presentation of the related diseases have been described worldwide. Based on the geographical characteristics of Brazil and data from the literature, we have summarized the distribution of seroprevalence in blood donors in different states around the country, as well as the incidence of ATL in regards to the endemic foci. ATL in Brazil has the same characteristics as those described elsewhere, but is reported more frequently at a younger age. In order to better evaluate ATL in Brazil, a registry has been established at the several hematologic centers under the sponsorship of the Instituto Nacional de Cancer and the Brazilian Society of Hematology and Hemotherapy, for the purpose of recording all cases originally diagnosed in Brazil.
Full text:
1
Index:
LILACS
Main subject:
Leukemia-Lymphoma, Adult T-Cell
Type of study:
Incidence_studies
/
Prognostic_studies
/
Risk_factors_studies
Limits:
Adult
/
Female
/
Humans
Country/Region as subject:
America do sul
/
Brasil
Language:
En
Journal:
São Paulo med. j
Journal subject:
Cirurgia Geral
/
Cincia
/
Ginecologia
/
MEDICINA
/
Medicina Interna
/
Obstetr¡cia
/
Pediatria
/
Sa£de Mental
/
Sa£de P£blica
Year:
1996
Type:
Article