Effect of urea on biomimetic aggregates
Braz. j. med. biol. res
;
30(2): 179-85, Feb. 1997. ilus, tab, graf
Article
in English
| LILACS
| ID: lil-188424
ABSTRACT
The effect of urea on biomimetic aggregates (aqueous and reversed micelles, vesicles and monolayers) was investigated to obtain insights into the effect of the denaturant on structured macromolecules. Direct evidence obtained from light scattering (static and dynamic), monolayer maximum isothermal compression and ionic conductivity measurements, together with indirect evidence from fluorescence photodissociation, fluorescence suppression, and thermal reactions, strongly indicates the direct interaction mechanism of urea with the aggregates. Preferential solvation of the surfactant headgroups by urea results in an increase in the monomer dissociation degree (when applied), which leads to an increase in the area per headgroup and also in the loss of counterion affinities.
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Surface-Active Agents
/
Urea
/
Coated Vesicles
/
Micelles
Limits:
Humans
Language:
English
Journal:
Braz. j. med. biol. res
Journal subject:
Biology
/
Medicine
Year:
1997
Type:
Article
/
Congress and conference
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