Effect of protein malnutrition on the glycolytic and glutaminolytic enzyme activity of rat thymus and mesenteric lymph nodes
Braz. j. med. biol. res
;
30(6): 719-22, jun. 1997. tab
Article
in English
| LILACS
| ID: lil-194170
RESUMO
The activity of important glycolytic enzymes (hexokinase, phosphofructokinase, aldolase, phosphohexoseisomerase, pyruvate kinase and lactate dehydrogenase) and glutaminolytic enzymes (phosphate-dependent glutaminase) was determined in the thymus and mesenteric lymph nodes of wistar rats submited to protein malnutrition (6 percent protein in the diet rather than 20 percent) from conception to 12 weeks after birth. The wet weight (g) of the thymus and mesenteric lymph nodes decreased due to protein malnutrition by 87 percent (from 0.30 + 0.05 to 0.04 + 0.01) and 75 percent (0.40 + 0.04 to 0.10 + 0.02), respectively. The protein content was reduced only in the thymus from 102.3 + 4.4 (control rats) to 72.6 + 6.6 (malnourished rats). The glycolytic enzymes were not affected by protein malnutrition, but the glutaminase activity of the thymus and lymph nodes was reduced by halfing in protein-malnourished rats as compared to controls. This fact may lead to a decrease in the cellularity of the organ and thus in its size, weight and protein content.
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Pyruvate Kinase
/
Thymus Gland
/
Dietary Proteins
/
Protein-Energy Malnutrition
/
Phosphofructokinase-1
/
Fructose-Bisphosphate Aldolase
/
Glucose
/
Glucose-6-Phosphate Isomerase
/
Glutaminase
/
Glutamine
Limits:
Animals
Language:
English
Journal:
Braz. j. med. biol. res
Journal subject:
Biology
/
Medicine
Year:
1997
Type:
Article
Similar
MEDLINE
...
LILACS
LIS