Enfermedad venooclusiva hepática asociada a terapia con azatioprina en un paciente trasplantado renal / Hepatic veno-occlusive disease associated to the use of azathioprine in a renal transplant recipient
Rev. méd. Chile
;
124(12): 1489-91, dic. 1996. tab
Article
in Spanish
| LILACS
| ID: lil-194798
ABSTRACT
We report a 30 years old male, recipient of a kidney allograft and treated with azathioprine, who 18 days after transplantation had a clinically asymptomatic elevation of total bilirrubin and alkaline phosphatases. Nineteen months later, he presented with mild ascites, with a total bilirrubin of 3.5 mg/dl, alkaline phosphatases of 308 U/L (normal <170 U/L) and a prothrombin time at 55 percent of control. A liver biopsy showed sinusoidal and perivenular fibrosis without inflammation, compatible with chronic venous obstruction. Hepatic veno-occlusive disease is an infrequent complication of azathioprine use
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Index:
LILACS (Americas)
Main subject:
Azathioprine
/
Hepatic Veno-Occlusive Disease
Type of study:
Risk factors
Limits:
Adult
/
Humans
/
Male
Language:
Spanish
Journal:
Rev. méd. Chile
Journal subject:
Medicine
Year:
1996
Type:
Article
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