Aborto espontáneo: estudio citogenético en 609 casos / Spontaneous abortion: cytogenetical study in 609 cases
Rev. méd. Chile
;
125(3): 317-22, mar. 1997. tab
Article
in Spanish
| LILACS
| ID: lil-194834
ABSTRACT
Cromosomal abnormalities are the most frequent cause of first trimester spontaneous abortions (SA). During the period Sep. 1989 through May 1996 we have cytogenetically studied 640 embrionic tissue samples obtained from cases of SA. Of these, 609 samples (95,1 percent) were successfully karyotyped. An abnormal karyotype was observed in 388 cytogenetically normal and abnormal embryos. The most frequent abnormalities detected were autosomal trisomies (239/388 [61.6 percent]) followed by triploidy (62 cases, 16 percent), monosomies (41 cases, 10.6 percent) and teraploidy (17 cases, 4.4 percent). The single most common anomaly observed was trisomy 16 (73 cases, 18.8 percent). The frequency of trisomies, with the exception trisomy 16, was related with advanced maternal age
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Index:
LILACS (Americas)
Main subject:
In Vitro Techniques
/
Abortion, Spontaneous
/
Chromosome Aberrations
/
Cytogenetics
Language:
Spanish
Journal:
Rev. méd. Chile
Journal subject:
Medicine
Year:
1997
Type:
Article
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