Permeabilidad intestinal en alcohólicos sin daño hepático / Intestinal permeability in alcoholics without hepatic damage
Rev. méd. Chile
;
125(6): 653-8, jun. 1997. tab, graf
Article
in Spanish
| LILACS
| ID: lil-197762
ABSTRACT
Methods:
Thirty seven male subjects were studied, 18 controls and 19 alcoholic All subjects underwent an anthropometric assessment and dietary history. Lactulose/mannitol test was performed during the third day of abstinence in alcoholics. After an 8 hour overnight fast, subjects drank 200 ml of a solution containing 56 g lactulose and 5 g mannitol. Subsequently, urine was collected during the following 5 hours, where both sugars were measured by gas chromatography.Results:
Median values of lactulose/mannitol ratio were similar in alcoholics and controls (0.011, range 0.005-0.071 vs 0.014, range 0.005-0.027 respectively). However, absolute urinary excretion of both lactulose and mannitol was lower in alcholics. There was no relationship betwwen nutritional status and urinary excretion of lactulose, mannitol or lactulose/mannitol ratio. Conslusion In this alcoholic patients, no changes were observed in intestinal permability
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Index:
LILACS (Americas)
Main subject:
Alcoholism
/
Gastrointestinal Motility
/
Intestinal Mucosa
Limits:
Adult
/
Humans
/
Male
Language:
Spanish
Journal:
Rev. méd. Chile
Journal subject:
Medicine
Year:
1997
Type:
Article
/
Project document
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