Multistep carcinogenesis and genital papillomavirus infection: implications for diagnosis and vaccines
Arch. med. res
;
25(2): 265-72, 1994. tab, ilus
Article
in English
| LILACS
| ID: lil-198811
ABSTRACT
Activated cellular oncogenes (myc and ras, for example) and inactivated anti-oncogenes (p53 or Rb) participate in multistep carcinogenesis. In addition, some high risk human papillomaviruses (HPV) are also involved in uterine cervix carcinomas. Typification of HPV is important for clinical diagnosis. Unravelling the complexities of the immune system and understanding the biochemistry and molecular genetics of cellular oncogenes and tumor viruses have opened up new possibilities for vaccination
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Index:
LILACS (Americas)
Main subject:
Papillomaviridae
/
Uterus
/
Carcinoma
/
Genital Neoplasms, Female
/
Neoplasms
Type of study:
Diagnostic study
Language:
English
Journal:
Arch. med. res
Journal subject:
Medicine
Year:
1994
Type:
Article
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