Genetic control of innate and acquired immunity
Ciênc. cult. (Säo Paulo)
;
46(5/6): 363-7, Sept.-Dec. 1994. tab
Article
in English
| LILACS
| ID: lil-199864
RESUMO
Host defense against infection depends on both specific and nonspecific mechanisms.The lines of mice genetically selected for high (H) or low (L) antibody responsiveness and for the maximal (AIR max.) or minimal (AIR min.) acute inflammatory response, in which the opposite extreme potentialities have been clearly defined, ofter an appropriate model for investigation of the major genetic and environmental factors of resistance to infections. The alternative advantagens of the extreme phenotypes such as efficacy of specific and nonspecific immunity in natural populations are discussed.
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Index:
LILACS (Americas)
Main subject:
Immune System
/
Immunity, Innate
Type of study:
Prognostic study
Limits:
Animals
Language:
English
Journal:
Ciênc. cult. (Säo Paulo)
Journal subject:
Science
Year:
1994
Type:
Article
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