Molecular biolgy and skin cancer

RESUMO

Nowadays, molecular biology is undoubtedly recognized as an important factor in skin cancer. Exposure to solar UVB gives rise to mutations in oncogenes and tumor suppressor genes that initiate the molecular cascade leading to skin cancer. For human malignant melanoma, several oncogenes have been proposed as being involved in the transformation process, but no consistent pattern of oncogene activation has yet been identified. Thus, molecular biology can be useful in skin cancer diagnosis, prognosis, and treatment.