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Cytokines in the modulation of eosinophilia
Mem. Inst. Oswaldo Cruz ; 92(supl.2): 109-14, Dec. 1997. tab, graf
Article in English | LILACS | ID: lil-202021
RESUMO
In this review we discuss our recently results showing interleukin 5 (IL-5) involvement in eosinophil migration and in the maintenance of eosinophilia in blood, bone marrow, lung and peritoneal cavity, in a visceral larva migrans syndrome model using guinea-pigs infected with Toxocara canis. We also describe the sequential release of TNF-a and IL-8 during the course of infection, and the interaction between these cytokines and IL-5 during infection. Finally, we propose a new biological role for IL-5, at least in our model, as a modulator of IL-8 release and secretion.
Subject(s)
Full text: Available Index: LILACS (Americas) Main subject: Cytokines / Toxocara canis / Eosinophils Type of study: Prognostic study Limits: Animals Language: English Journal: Mem. Inst. Oswaldo Cruz Journal subject: Tropical Medicine / Parasitology Year: 1997 Type: Article / Congress and conference

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Full text: Available Index: LILACS (Americas) Main subject: Cytokines / Toxocara canis / Eosinophils Type of study: Prognostic study Limits: Animals Language: English Journal: Mem. Inst. Oswaldo Cruz Journal subject: Tropical Medicine / Parasitology Year: 1997 Type: Article / Congress and conference