Cytokines in the modulation of eosinophilia
Mem. Inst. Oswaldo Cruz
;
92(supl.2): 109-14, Dec. 1997. tab, graf
Article
in English
| LILACS
| ID: lil-202021
RESUMO
In this review we discuss our recently results showing interleukin 5 (IL-5) involvement in eosinophil migration and in the maintenance of eosinophilia in blood, bone marrow, lung and peritoneal cavity, in a visceral larva migrans syndrome model using guinea-pigs infected with Toxocara canis. We also describe the sequential release of TNF-a and IL-8 during the course of infection, and the interaction between these cytokines and IL-5 during infection. Finally, we propose a new biological role for IL-5, at least in our model, as a modulator of IL-8 release and secretion.
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Cytokines
/
Toxocara canis
/
Eosinophils
Type of study:
Prognostic study
Limits:
Animals
Language:
English
Journal:
Mem. Inst. Oswaldo Cruz
Journal subject:
Tropical Medicine
/
Parasitology
Year:
1997
Type:
Article
/
Congress and conference
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