Myelodysplastic syndromes (MDS): prognostic factors and scoring systems
São Paulo med. j
;
115(5): 1537-41, set.-out. 1997. tab
Article
in English
| LILACS
| ID: lil-209336
RESUMO
To evaluate the score systems of Cassano and Sanz and suggest a new one. Design:
Case series. Location Teaching hospitals EPM UNIFESP and Faculdade de Medicina de Botucatu.Participants:
59 patients diagnosed from 1979 to 1992. Intervention Evaluation of clinical-laboratorial data. Measurement Statistical comparison, uni and multivariate analysis and actuarial survival curves.Results:
Cassano's system divided the patients into high and low risk (p=0.0966) while Sanz's gave high, intermediate and low risk (p=0.0108). The univariate analysis showed hemoglobin, WBC count, E/M ratio, liver size and blast percentage in BM as statistically significant. The multivariate analysis showed blast percentage in BM (p=0.004) and Hb (p=0.050) as signigicant. Our system, considering the multivariate analysis data, divided the patients into high, intermediate and low risk (p=0.0038).Conclusions:
Sanz's system was more functional than Cassano's, while ours showed predictive survival value and ease of use in clinical practice.
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Myelodysplastic Syndromes
Type of study:
Observational study
/
Prognostic study
/
Risk factors
Limits:
Adolescent
/
Adult
/
Aged80
/
Female
/
Humans
Language:
English
Journal:
São Paulo med. j
Journal subject:
Cirurgia Geral
/
Cincia
/
Ginecologia
/
Medicine
/
Medicina Interna
/
Obstetr¡cia
/
Pediatria
/
Sa£de Mental
/
Sa£de P£blica
Year:
1997
Type:
Article
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