Expression and cytokine secretion in the states of immune reactivation in leprosy
Braz. j. med. biol. res
;
31(1): 69-76, Jan. 1998.
Article
in English
| LILACS
| ID: lil-212540
ABSTRACT
Leprosy is a chronic inflammatory disease caused by Mycobacterium leprae. The human response to this pathogen exhibits intriguing aspects which are up to now not well understood. The present study discusses the probable mechanisms involved in T cell-specific unresponsiveness observed in lepromatous patients. Analysis of the cytokine profile either in blood leukocytes or in skin specimens taken from leprosy lesions indicates that some parameters of Th1 immune response are present in lepromatous patients under reactional states.
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Cytokines
/
Leprosy
Limits:
Humans
Language:
English
Journal:
Braz. j. med. biol. res
Journal subject:
Biology
/
Medicine
Year:
1998
Type:
Article
/
Congress and conference
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