El electrocardiograma del acure. Cambios inducidos por la administracion aguda de b-metil digoxina / The electrocardiogram of the guinea pig. Changes induced by the beta-methyl digoxin acute administration
Acta cient. venez
;
45(3): 207-13, 1994. tab, graf
Article
in Spanish
| LILACS
| ID: lil-217162
ABSTRACT
In this study we describe the normal electrocardiogram of the Guinea pig (Cavia porcellus), including the correlation between cardiac frequency and the Q-T interval. We studied the acute changes induced by an intraperitoneal dose of beta-methyl digoxin (0.2 mg). The drug produced a significant decrease in cardiac frequency and a significant prolongation of the P-R interval. It did not change the QRS duration or its position on the frontal plane. The Q-T interval, corrected by cardiac frequency, showed a tendency to decrease with treatment, but this change did not reach significance. The drug caused characteristic changes in ventricular repolarization the T wave changed its polarity and S-T segment shifted to negative potential (between 0.05 and 0.15 mV). The possible origin of these observation is discussed
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Index:
LILACS (Americas)
Main subject:
Cardiotonic Agents
/
Electrocardiography
/
Heart Rate
/
Medigoxin
Limits:
Animals
Language:
Spanish
Journal:
Acta cient. venez
Journal subject:
Science
Year:
1994
Type:
Article
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