Variations in white blood count, thromboxane B2 levels and hematocrit in chronic venous hypertension
São Paulo med. j
;
116(3): 1721-6, May-Jun. 1998. tab
Article
in English
| LILACS
| ID: lil-224005
RESUMO
Objective:
To analyze variations in leukocyte count and thromboxane B2 production in the femoral vein of patients with chronic venous hypertension (CVH).Design:
Prospective clinical study, controlled, non randomized and open. Location Hospital das Cl[inicas, Faculdade de Medicina da Universidade de Sao Paulo, referral center, university hospital.Participants:
15 patients with recurring stasis ulcer were analyzed, selected randomly from the venous diseases outpatient center, and 4 without lower limb venous alterations were also analyzed. Intervention Blood samples from the femoral and brachial veins were drawn following supine and 45º reverse Trendelenburg. Main outcomesmeasures:
Direct leukocyte count and analysis of the thomboxane B2 with enzyme linked immunosorbent assay test.Results:
After 30 minutes in reverse Trendelenburg, patients with CVH showed a leukocyte count reduced by +27 per cent (p=0.02) and thromboxane B2 levels increased by +158 per cent (p=0.02).Conclusions:
We suggest that future studies of medications for stasis ulcers include their effects on leukocyte entrapment and thromboxane B2 production in the lower limb venous system.
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Thromboxane B2
/
Varicose Ulcer
/
Hematocrit
/
Leukocyte Count
Type of study:
Controlled clinical trial
/
Observational study
Limits:
Adolescent
/
Adult
/
Female
/
Humans
/
Male
Language:
English
Journal:
São Paulo med. j
Journal subject:
Cirurgia Geral
/
Cincia
/
Ginecologia
/
Medicine
/
Medicina Interna
/
Obstetr¡cia
/
Pediatria
/
Sa£de Mental
/
Sa£de P£blica
Year:
1998
Type:
Article
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