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Immunity to the 60kD heat shock proteins
Neuer, Andreas; Giraldo, Paulo; Spandorfer, Steven D; Dieterle, Stefan; He, Zhiing; Kiesel, Ludwig; Witkin, Steven S.
  • Neuer, Andreas; Cornell University Medical College, USA. Department of Obstetrics and Gynecology.
  • Giraldo, Paulo; UNICAMP, Säo Paulo. Department and Obstetrics and Gynecology.
  • Spandorfer, Steven D; Cornell University Medical College, USA. Department of Obstetrics and Gynecology.
  • Dieterle, Stefan; University of Witten-Herdecke, Germany. Institute of Gynecological endocrinology and Reproductive Medicine.
  • He, Zhiing; Cornell University Medical College, USA. Department of Obstetrics and Gynecology.
  • Kiesel, Ludwig; University of Tübingen, Germany. Women's Hospital.
  • Witkin, Steven S; Cornell University Medical College, USA. Department of Obstetric and Gynecology.
DST j. bras. doenças sex. transm ; 10(1): 17-21, jan.-fev. 1998. tab
Article in English | LILACS | ID: lil-224861
RESUMO
A brief review on the role of the heat shock proteins (hsp), their common properties and possible consequences for early pregnancy development is described. The 60kD hsp plays an important role as immunogenic antigen of many microbial pathogens and possibly in postinfectious autoimmunity. The immune responce to hsp may cause pregnancy failure. The consequences of previous sensitization to microbial hsp and the effects of human autoantibodies to hsp, are demonstrated in a mouse embryo culture model.
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Index: LILACS (Americas) Main subject: Reproduction / In Vitro Techniques / Chaperonin 60 / Immunity Limits: Animals Language: English Journal: DST j. bras. doenças sex. transm Journal subject: Sexually Transmitted Diseases Year: 1998 Type: Article

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Index: LILACS (Americas) Main subject: Reproduction / In Vitro Techniques / Chaperonin 60 / Immunity Limits: Animals Language: English Journal: DST j. bras. doenças sex. transm Journal subject: Sexually Transmitted Diseases Year: 1998 Type: Article