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The rebound effect in the treatment of complex hemangioma with interferon alpha 2A
Anger, Jaime; Carneiro, Ricardo Gama; Pinus, José; Ernesto, José Manoel; Faiwichow, Guido.
  • Anger, Jaime; Hospital Israelita Albert Einstein, Säo Paulo.
  • Carneiro, Ricardo Gama; Hospital Israelita Albert Einstein, Säo Paulo.
  • Pinus, José; Hospital Israelita Albert Einstein, Säo Paulo.
  • Ernesto, José Manoel; Hospital Israelita Albert Einstein, Säo Paulo.
  • Faiwichow, Guido; Hospital Israelita Albert Einstein, Säo Paulo.
São Paulo med. j ; 116(5): 1826-8, Sept.-Oct. 1998.
Article in English | LILACS | ID: lil-226005
ABSTRACT
The authors report the case of an infant with an extensive face hemangiona with subglottic airway obstruction which had been successfully treated with interferon alpha 2A but then reoccurred with the same dimensions and airway blockage after treatment was abruptly interrupted. The authors suggest the implementation of a standard procedure for the interruption of interferon alpha 2A treatment in order to avoid this rebound effect and advise on the need for further studies to properly evaluate dosage and administration parameters for interferon alpha 2A in the treatment of difficult hemangioma.
Subject(s)
Full text: Available Index: LILACS (Americas) Main subject: Facial Neoplasms / Interferon-alpha / Airway Obstruction / Hemangioma / Antineoplastic Agents Limits: Infant, Newborn Language: English Journal: São Paulo med. j Journal subject: Cirurgia Geral / Ciˆncia / Ginecologia / Medicine / Medicina Interna / Obstetr¡cia / Pediatria / Sa£de Mental / Sa£de P£blica Year: 1998 Type: Article Affiliation country: Brazil

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Full text: Available Index: LILACS (Americas) Main subject: Facial Neoplasms / Interferon-alpha / Airway Obstruction / Hemangioma / Antineoplastic Agents Limits: Infant, Newborn Language: English Journal: São Paulo med. j Journal subject: Cirurgia Geral / Ciˆncia / Ginecologia / Medicine / Medicina Interna / Obstetr¡cia / Pediatria / Sa£de Mental / Sa£de P£blica Year: 1998 Type: Article Affiliation country: Brazil