Características clínicas y de laboratorio de pacientes con reflujo gastroesofágico crónico patológico / Clinical and laboratory features of patients with chronic gastroesophageal reflux
Rev. méd. Chile
;
126(7): 769-80, jul. 1998. ilus, tab
Article
in Spanish
| LILACS
| ID: lil-231518
ABSTRACT
Background:
Sixty percent of adults has typical symptoms of gastroesophageal reflux in Chile.Aim:
To report the clinical and laboratory features of patients with gastroesophageal reflux. Patients andmethods:
Five hundred thirty four patients (255 male) with gastroesophageal reflux were included in a prospective protocol that included clinical analysis, manometry and endoscopy in all patients, barium swallow in 427, scintigraphy in 195, acid reflux test in 359, 24 h pH in 175, and differential potential of gastroesophageal mucosa in 73 patients.Results:
There was no correlation between the severity of symptoms and the endoscopical severity. Patients with Barret esophagus were 12 years older, were male in a greater proportion and had a higher proportion of manometrically incompetent sphincters than patients with esophageal reflux but without esophagitis or with erosive esophagitis. Severity of acid reflux, measured with 24 h pH monitoring was proportional to the endoscopical damage of the mucosa. There was a close relationship between the mucosal change limit determined with differential potentials and with endoscopy. No short esophagi were found.Conclusions:
Patients with symptoms of gastroesophageal reflux must be assessed using several objective measures to determine the severity of their pathological alterations
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Gastroesophageal Reflux
Type of study:
Practice guideline
/
Observational study
/
Risk factors
Limits:
Adult
/
Female
/
Humans
/
Male
Language:
Spanish
Journal:
Rev. méd. Chile
Journal subject:
Medicine
Year:
1998
Type:
Article
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