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Axotomy increases NADPH-diaphorase activity in the dorsal root ganglia and lumbar spinal cord of the turtle Trachemys dorbigni
Partata, W. A; Krepsky, A. M. R; Marques, M; Achaval, M.
  • Partata, W. A; Universidade Federal do Rio Grande do Sul. Instituto de Ciências Básicas e da Saúde. Departamento de Fisiologia.
  • Krepsky, A. M. R; Universidade Federal do Rio Grande do Sul. Instituto de Ciências Básicas e da Saúde. Departamento de Fisiologia.
  • Marques, M; Universidade Federal do Rio Grande do Sul. Instituto de Ciências Básicas e da Saúde. Departamento de Fisiologia.
  • Achaval, M; Universidade Federal do Rio Grande do Sul. Instituto de Ciências Básicas e da Saúde. Departamento de Ciências Morfológicas.
Braz. j. med. biol. res ; 32(4): 489-93, Apr. 1999. ilus
Article in English | LILACS | ID: lil-231743
ABSTRACT
Seven days after transection of the sciatic nerve NADPH-diaphorase activity increased in the small and medium neurons of the dorsal root ganglia of the turtle. However, this increase was observed only in medium neurons for up to 90 days. At this time a bilateral increase of NADPH-diaphorase staining was observed in all areas and neuronal types of the dorsal horn, and in positive motoneurons in the lumbar spinal cord, ipsilateral to the lesion. A similar increase was also demonstrable in spinal glial and endothelial cells. These findings are discussed in relation to the role of nitric oxide in hyperalgesia and neuronal regeneration or degeneration.
Subject(s)
Full text: Available Index: LILACS (Americas) Main subject: Spinal Cord / Turtles / Axotomy / Ganglia, Spinal / NADPH Dehydrogenase Limits: Animals Language: English Journal: Braz. j. med. biol. res Journal subject: Biology / Medicine Year: 1999 Type: Article / Project document

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Full text: Available Index: LILACS (Americas) Main subject: Spinal Cord / Turtles / Axotomy / Ganglia, Spinal / NADPH Dehydrogenase Limits: Animals Language: English Journal: Braz. j. med. biol. res Journal subject: Biology / Medicine Year: 1999 Type: Article / Project document