Amyotropic lateral sclerosis with dementia: case report
Arq. neuropsiquiatr
;
57(2A): 277-83, jun. 1999. ilus
Article
in English
| LILACS
| ID: lil-234463
RESUMO
A patients is described in whom a profound and rapidly progressive dementia occurred in association with clinical features of amyotrophic lateral sclerosis. A magnetic resonance imaging showed signs of frontal and especially left temporal atrophy. The pattern of dementia indicated impaired frontotemporal lobe functions, evidenced by reduced tracer uptake in the frontotemporal lobes on brain single photon emission computed tomography. Neuropathological examination in this patient revealed mild frontotemporal atrophy with spongiform changes and neuronal loss affecting mainly layers II and III of the frontotemporal cortices. There was atrophy of the hypoglossal nuclei. The spinal cord changes were consistent with motor neuron disease. The patient showed an irreversible and progressive course. A review of the relevant literature was made.
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Dementia
/
Amyotrophic Lateral Sclerosis
Limits:
Aged
/
Female
/
Humans
Language:
English
Journal:
Arq. neuropsiquiatr
Journal subject:
Neurology
/
Psychiatry
Year:
1999
Type:
Article
Affiliation country:
Brazil
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