Validity of behavioral and physiologic parameters for acute pain assessment of term newborn infants

RESUMO

The subjectivity of pain causes enormous difficultines in evaluating neonatal pain with a single, pratical and easy-to-apply tool. Pain evaluation in the neonatal period should be performed by valid, safe, useful and feasible methods. Objective: To evaluate the validity of the Neonatal Facial Coding System (NFCS), Neonatal Infant Pain Scale (NIPS), heart rate (HR) and O2 saturation (O2 sat) for neonatal pain assessment. Design: Prospective double-blind randomized trial. Setting: A secondary level maternity hospital. Participants: 70 healthy neonates requiring bilirubin dosage were randomly assigned to receive a venous puncture (P n=33, BW 3.2kg, SD 0.6; GA 39wk, SD 1; 59h of life, SD 25) or an alcohol swab friction (F n=37; BW 3.1kg, SD 0.5; GA 39wk, SD 1; 52h of life, SD 17). Intervention All measurements were taken prior to (PRE), during (TO), and 1 (T1), 3(T3), 5(T5) and 10 (T10) minutes after the procedure. Measurements A neonatologist evaluated NFCS, NIPS, HR and O2 sat by pulse oxymetry. Results: Median NFCS and NIPS results at TO, T1 and T3 were higher in P group, compared to F. More P neonates presented NFCS > 2 and/or NIPS > 3 at T0, T1 and T3. HR was lower in P group at T1. Average O2 sat was above 90 per cent during the whole study period in both groups. Conclusion: NFCS and NIPS are suitable instruments for neonatal pain evaluation. Heart rate and O2 saturation can be used only as auxiliary methods.