Experimental infection of canine peritoneal macrophages with visceral and dermotropic Leishmania strains
Mem. Inst. Oswaldo Cruz
;
94(5): 645-8, Sept. 1999. ilus
Article
in English
| LILACS
| ID: lil-241325
RESUMO
A study was carried out using macrophages cultured from the peritoneal exudate of dogs infected in vitro with three species of Leishmania L. (L.) chagasi, L. (Viannia) braziliensis and L. (L.) amazonensis with the aim of investigating the growth kinetics and infectivity of these species in the host cell. Results were expressed as the percentage of macrophages infected measured at 24 hr intervals over six days in RPMI - 1640 culture medium at a temperature of 34-35oC. The findings open the possibility of using canine peritoneal cells as a model for the screenning of leishmanicide drugs and to study the pathogenesis of these species.
Full text:
Available
Index:
LILACS (Americas)
Main subject:
In Vitro Techniques
/
Macrophages, Peritoneal
/
Leishmania
Type of study:
Prognostic study
Limits:
Animals
Language:
English
Journal:
Mem. Inst. Oswaldo Cruz
Journal subject:
Tropical Medicine
/
Parasitology
Year:
1999
Type:
Article
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