Asociación entre grupo sanguíneo Kidd y malformaciones congénitas / Association between Kidd blood group and congenital malformations
Rev. méd. Chile
;
126(11): 1311-5, nov. 1998. tab, graf
Article
in Spanish
| LILACS
| ID: lil-243722
ABSTRACT
Background:
Since the discovery of blood groups, an association between these genetic polymorphisms and pathological phenotypes has been searched, looking for factors involved in the pathogenesis of diseases or biological population mechanisms that maintain these polymorphisms. In previous reports, we have described some associations between erythrocytic genetic marker segregation and the presence of congenital malformations.Aim:
To explore the association between Kidd blood group and congenital malformations. Patients andmethods:
One hundred twenty two malformed newborns and their mothers and 136 normal newborns, seen at the Clinical Hospital of the University of Chile, were studied.Results:
Kidd blood group segregation distortions were found among male malformed newborns, that were not present in normal newborns. Among mothers of both groups of newborns, a paucity of heterozygous for this system was found.Conclusions:
The association found between a blood group and congenital malformations, allows to state that malformed children have a different genetic background, when compared to normal children
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Index:
LILACS (Americas)
Main subject:
Congenital Abnormalities
/
Kidd Blood-Group System
Type of study:
Observational study
/
Risk factors
Limits:
Adult
/
Female
/
Humans
/
Male
/
Infant, Newborn
Language:
Spanish
Journal:
Rev. méd. Chile
Journal subject:
Medicine
Year:
1998
Type:
Article
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