Juvenile Huntington's disease confirmed by genetic examination in twins
Arq. neuropsiquiatr
;
57(3B): 867-9, set. 1999. ilus
Article
in English
| LILACS
| ID: lil-247399
ABSTRACT
Early-onset Huntington's disease (HD) occurs in approximatley 10 per cent of HD's cases. We report juvenile HD in phenotypically identical twins, evaluated by history, clinical and neurologic examination, minimental state examination, blood laboratory exams, cerebrospinal fluid examination, skull computed tomography, and genetic examination for HD. Patients had the akinetic-rigid variety (Westphal variant) of the disease and paternal inheritance. The laboratory workup confirmed the clinical diagnosis of HD, which adds this report to the rare cases of HD in twins reported in the literature.
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Twins
/
Huntington Disease
Limits:
Female
/
Humans
Language:
English
Journal:
Arq. neuropsiquiatr
Journal subject:
Neurology
/
Psychiatry
Year:
1999
Type:
Article
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