Serum cytokine levels in autoimmune and non-autoimmune hyperthyroid states
Braz. j. med. biol. res
;
33(1): 65-9, Jan. 2000.
Article
in English
| LILACS
| ID: lil-252258
ABSTRACT
Although the role of interleukin-2 (IL-2) and interferon gamma (yIFN) is still poorly understood in hyperthyroid diseases, it is reasonable to assume that these cytokines may be present at higher levels in Graves' disease (GD) than in other primarily non-autoimmune thyroid diseases. In order to look for an easy method to distinguish GD from primarily non-autoimmune causes of hyperthyroidism, we compared 13 healthy individuals with 21 treated and untreated hyperthyroid GD patients and with 19 patients with hyperthyroidism due to other etiologies 7 cases of multinodular goiter, 5 cases of excessive hormone replacement and 7 cases of amiodarone-associated hyperthyroidism. All patients presented low TSH levels and a dubious clinical thyroid state. We found a good correlation between TSH and serum IL-2 levels (r = 0.56; P
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Thyrotropin
/
Graves Disease
/
Cytokines
/
Interferon-gamma
/
Interleukin-2
/
Hyperthyroidism
Type of study:
Diagnostic study
/
Etiology study
Limits:
Adolescent
/
Adult
/
Child
/
Female
/
Humans
Language:
English
Journal:
Braz. j. med. biol. res
Journal subject:
Biology
/
Medicine
Year:
2000
Type:
Article
Similar
MEDLINE
...
LILACS
LIS