Alternative mitochondrial functions in cell physiopathology: beyond ATP production
Braz. j. med. biol. res
;
33(2): 241-50, Feb. 2000.
Article
in English
| LILACS
| ID: lil-252302
ABSTRACT
It is well known that mitochondria are the main site for ATP generation within most tissues. However, mitochondria also participate in a surprising number of alternative activities, including intracellular Ca2+ regulation, thermogenesis and the control of apoptosis. In addition, mitochondria are the main cellular generators of reactive oxygen species, and may trigger necrotic cell death under conditions of oxidative stress. This review concentrates on these alternative mitochondrial functions, and their role in cell physiopathology
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Adenosine Triphosphate
/
Calcium
/
Reactive Oxygen Species
/
Apoptosis
/
Mitochondria
Language:
English
Journal:
Braz. j. med. biol. res
Journal subject:
Biology
/
Medicine
Year:
2000
Type:
Article
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