Avaliaçäo laboratorial do indivíduo hipertenso: validade das principais diretrizes em hipertensäo / Laboratory assessment of the hypertensive individual: value of the main guidelines for high blood pressure

RESUMO

Objective - To determine if abnormal laboratory findings are more common in individuals with hypertension and in those with other risk factors, such as obesity, smoking and alchol ingestion. Methods - A study was carried out in the general outpatient clinics of a university hospital (145 individuals without previous diagnosis of hypertension) and the following variables were assessed: high blood pressure (as defined by the VI Joint National Committee on Prevention, Detection and Treatment of High Blood Pressure - VI JNC), obesity [calculated using body mass index (BMI)], tobacco use, and alcoholic ingestion. The laboratory examinations consisted of the following tests: hemogram, glycemia, uric acid, potassium, total/HDL-fraction cholesterol, triglycerides, calcium and creatinine. Results - High blood pressure was not associated with a higher number of abnormal laboratory tests. Hypertensive individuals with a BMI = 25kg/m2 or normotensive obese individuals, however, had a higher frequency of diabetes (12X), hypertriglyceridemia (3X), and hypercholesterolemia (2X), as compared with hypertensive individuals with BMI <25kg/m2 and preobese/normal weight normotensive individuals. Conclusion - High blood pressure is not associated with a higher frequency of abnormal laboratory tests. The association of high blood pressure and obesity, however, increases the detection of diabetes and dyslipidemias.