Entry, dispersion and differentiation of microglia in the developing central nervous system
An. acad. bras. ciênc
;
72(1): 91-102, mar. 2000.
Article
in English
| LILACS
| ID: lil-259484
ABSTRACT
Microglial cells within the developing central nervous system (CNS) originate from mesodermic precursors of hematopoietic lineage that enter the nervous parenchyma from the meninges, ventricular space and/or blood stream. Once in the nervous parenchyma, microglial cells increase in number and disperse throughtout the CNS; these cells finally differentiate to become fully ramified microglial cells. In this article we review present knowledge on these phases of microglial development and the factors that probably influence them.
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Central Nervous System
/
Microglia
Limits:
Animals
/
Humans
Language:
English
Journal:
An. acad. bras. ciênc
Journal subject:
Science
Year:
2000
Type:
Article
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