A síndrome de Holt-Oram revisitada: dois casos em uma mesma família / Holt-Oram syndrome revisited: two patients in the same family
Arq. bras. cardiol
;
73(5): 429-34, Nov. 1999. ilus
Article
in Portuguese, English
| LILACS
| ID: lil-261164
RESUMO
Holt-Oram syndrome was first described in 1960 as an association of familial heart disease and musculoskeletal abnormalities. The most important findings include atrial septal defects, atrioventricular conduction abnormalities, vascular hypoplasia, and upper limb musculoskeletal deformities. We report two patients with this syndrome in the same family and discuss the variability of the musculoskeletal abnormalities and their association with the cardiac morphologic defects. Both patients in this study had associated eosinophilia, which has not been reported in the literature.
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Thumb
/
Abnormalities, Multiple
/
Hand Deformities, Congenital
/
Heart Defects, Congenital
Type of study:
Diagnostic study
Limits:
Adult
/
Humans
/
Male
Language:
English
/
Portuguese
Journal:
Arq. bras. cardiol
Journal subject:
Cardiology
Year:
1999
Type:
Article
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