Strategies by which some pathogenic trichomonads integrate diverse signals in the decision-marking process
An. acad. bras. ciênc
;
72(2): 173-86, Jun. 2000.
Article
in English
| LILACS
| ID: lil-262041
RESUMO
The interaction between each one of Trichomonas vaginalis and Tritrichomonas foetus with their hosts is a complex process in which components associated to the cell surfaces of both parasites and host epithelial cells, and also to soluble components found in vaginal/urethral secretions, are involved. Either cytoadhesion or the cytotoxicity exerted by parasites to host cells can be dictated by virulence factors such as adhesins, cysteine proteinases, laminin-binding proteins, integrins, integrin-like molecules, a cell detachment factor, a pore-forming protein, and glycosidases among others. How trichomonads manipulate informations from the extracellular medium, transduce such informations, and respond to them by stimulating the activities of some surface molecules and/or releasing enzymes are the aspects concerning trichomonal virulence which are here briefly reviewed and discussed.
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Trichomonas
/
Trichomonas Infections
/
Signal Transduction
Type of study:
Prognostic study
Limits:
Animals
/
Female
/
Humans
/
Male
Language:
English
Journal:
An. acad. bras. ciênc
Journal subject:
Science
Year:
2000
Type:
Article
/
Project document
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