Vascular Ó1D-Adrenoceptors: Are they related to hypertension?
Arch. med. res
;
30(5): 347-52, sept.-oct. 1999. graf
Article
in English
| LILACS
| ID: lil-266543
ABSTRACT
Heterogenic of vascular Ó1D-adrenoceptor subtypes has been revealed by pharmacological and molecular biology studies (i.e., Ó1A- , Ó1B- , and Ó1D-adrenoceptors). The Ó1D-adrenoceptor subtype is predominantly involved in the contraction of a variety of vessels and its role in the control of blood pressure has been suggested, a phenomenon probably related to aging. Recent advances in the use of young pre-hypertensive rats and adult spontaneously hypertensive ratas with one kidney and Grollman-type renal hypertension suggest vascular Ó1D-adrenoceptor involvement in the increased blood pressure. The possible role of Ó1D-adrenoceptors in the genesis/maintenance of hypertension is discussed in this review
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Index:
LILACS (Americas)
Main subject:
Blood Vessels
/
Hypertension
Limits:
Animals
Language:
English
Journal:
Arch. med. res
Journal subject:
Medicine
Year:
1999
Type:
Article
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