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Neuromuscular blockade in children
Almeida, Joäo Fernando Lourenço de; Kalil Filho, W. Jorge; Troster, Eduardo J.
  • Almeida, Joäo Fernando Lourenço de; Universidade de Säo Paulo. Faculdade de Medicina. Hospital das Clínicas. Departamento de Pediatria. Säo Paulo. BR
  • Kalil Filho, W. Jorge; Universidade de Säo Paulo. Faculdade de Medicina. Hospital das Clínicas. Departamento de Pediatria. Säo Paulo. BR
  • Troster, Eduardo J; Universidade de Säo Paulo. Faculdade de Medicina. Hospital das Clínicas. Departamento de Pediatria. Säo Paulo. BR
Rev. Hosp. Clin. Fac. Med. Univ. Säo Paulo ; 55(3): 105-10, May-June 2000. tab, graf
Article in English | LILACS | ID: lil-273572
RESUMO
Neuromuscular blocking agents (NMBAs) have been widely used to control patients who need to be immobilized for some kind of medical intervention, such as an invasive procedure or synchronism with mechanical ventilation. The purpose of this monograph is to review the pharmacology of the NMBAs, to compare the main differences between the neuromuscular junction in neonates, infants, toddlers and adults, and moreover to discuss their indications in critically ill pediatric patients. Continuous improvement of knowledge about NMBAs pharmacology, adverse effects, and the many other remaining unanswered questions about neuromuscular junction and neuromuscular blockade in children is essential for the correct use of these drugs. Therefore, the indication of these agents in pediatrics is determined with extreme judiciousness. Computorized (Medline 1990-2000) and active search of articles were the mechanisms used in this review
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Full text: Available Index: LILACS (Americas) Main subject: Neuromuscular Blockade / Neuromuscular Blocking Agents Limits: Adult / Child / Child, preschool / Humans / Infant / Infant, Newborn Language: English Journal: Rev. Hosp. Clin. Fac. Med. Univ. Säo Paulo Journal subject: Medicine Year: 2000 Type: Article Affiliation country: Brazil Institution/Affiliation country: Universidade de Säo Paulo/BR

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Full text: Available Index: LILACS (Americas) Main subject: Neuromuscular Blockade / Neuromuscular Blocking Agents Limits: Adult / Child / Child, preschool / Humans / Infant / Infant, Newborn Language: English Journal: Rev. Hosp. Clin. Fac. Med. Univ. Säo Paulo Journal subject: Medicine Year: 2000 Type: Article Affiliation country: Brazil Institution/Affiliation country: Universidade de Säo Paulo/BR