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Conventional chemotherapy for acute myeloid leukemia: a Brazilian experience
Pagnano, Kátia Borgia Barbosa; Traina, Fabiola; Takahashi, Tatiana; Oliveira, Gislaine Borba; Rossini, Marta Soares; Lorand-Metze, Irene; Vigorito, Afonso Celso; Miranda, Eliana Cristina Martins; Souza, Cármino Antonio De.
  • Pagnano, Kátia Borgia Barbosa; Universidade Estadual de Campinas. Hematology and Hemotherapy Center. Campinas. BR
  • Traina, Fabiola; Universidade Estadual de Campinas. Hematology and Hemotherapy Center. Campinas. BR
  • Takahashi, Tatiana; Universidade Estadual de Campinas. Hematology and Hemotherapy Center. Campinas. BR
  • Oliveira, Gislaine Borba; Universidade Estadual de Campinas. Hematology and Hemotherapy Center. Campinas. BR
  • Rossini, Marta Soares; Universidade Estadual de Campinas. Hematology and Hemotherapy Center. Campinas. BR
  • Lorand-Metze, Irene; Universidade Estadual de Campinas. Hematology and Hemotherapy Center. Campinas. BR
  • Vigorito, Afonso Celso; Universidade Estadual de Campinas. Hematology and Hemotherapy Center. Bone Marrow Transplantation Unit. Campinas. BR
  • Miranda, Eliana Cristina Martins; Universidade Estadual de Campinas. Hematology and Hemotherapy Center. Bone Marrow Transplantation Unit. Campinas. BR
  • Souza, Cármino Antonio De; Universidade Estadual de Campinas. Hematology and Hemotherapy Center. Hematology and Hemotherapy Division. Campinas. BR
São Paulo med. j ; 118(6): 173-8, Nov. 2000. graf, tab
Article in English | LILACS | ID: lil-277625
ABSTRACT
CONTEXT Young patients affected by acute myeloid leukemia (AML) achieve complete remission (CR) using conventional chemotherapy in about 55-85 percent. However, 30 percent of patients fail to achieve CR and the remission duration is often only about 12 months. More intensive treatment after CR seems to be necessary in order to maintain CR and obtain a definitive cure. In Brazil, few reports have been published on this important subject.

OBJECTIVE:

The aim of this study was to describe a Brazilian experience in the treatment of "de novo" acute myeloid leukemia (AML) in younger adult patients (age < 60 years).

DESIGN:

Retrospective analysis.

SETTING:

University Hospital, Hematology and Hemotherapy Center, State University of Campinas, Brazil...
Subject(s)
Full text: Available Index: LILACS (Americas) Main subject: Antineoplastic Combined Chemotherapy Protocols / Leukemia, Myeloid Type of study: Observational study / Prognostic study / Risk factors Limits: Adolescent / Adult / Female / Humans / Male Country/Region as subject: South America / Brazil Language: English Journal: São Paulo med. j Journal subject: Cirurgia Geral / Ciˆncia / Ginecologia / Medicine / Medicina Interna / Obstetr¡cia / Pediatria / Sa£de Mental / Sa£de P£blica Year: 2000 Type: Article Affiliation country: Brazil Institution/Affiliation country: Universidade Estadual de Campinas/BR

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Full text: Available Index: LILACS (Americas) Main subject: Antineoplastic Combined Chemotherapy Protocols / Leukemia, Myeloid Type of study: Observational study / Prognostic study / Risk factors Limits: Adolescent / Adult / Female / Humans / Male Country/Region as subject: South America / Brazil Language: English Journal: São Paulo med. j Journal subject: Cirurgia Geral / Ciˆncia / Ginecologia / Medicine / Medicina Interna / Obstetr¡cia / Pediatria / Sa£de Mental / Sa£de P£blica Year: 2000 Type: Article Affiliation country: Brazil Institution/Affiliation country: Universidade Estadual de Campinas/BR