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Effect of leaf essential oil from Piper solmsianum C.DC. in mice behaviour
Moreira, Davyson L; Souza, Patrícia O; Kaplan, Maria Auxiliadora C; Pereira, Nuno A; Cardoso, Geraldo L; Guimaräes, Elsie F.
  • Moreira, Davyson L; Universidade Federal do Rio de Janeiro. Núcleo de Pesquisas de Produtos Naturais. Rio de Janeiro. BR
  • Souza, Patrícia O; Universidade Federal do Rio de Janeiro. Núcleo de Pesquisas de Produtos Naturais. Rio de Janeiro. BR
  • Kaplan, Maria Auxiliadora C; Universidade Federal do Rio de Janeiro. Núcleo de Pesquisas de Produtos Naturais. Rio de Janeiro. BR
  • Pereira, Nuno A; Universidade Federal do Rio de Janeiro. Departamento de Farmacologia Básica e Clínica. Rio de Janeiro. BR
  • Cardoso, Geraldo L; Universidade Federal do Rio de Janeiro. Departamento de Farmacologia Básica e Clínica. Rio de Janeiro. BR
  • Guimaräes, Elsie F; Jardim Botânico do Rio de Janeiro. BR
An. acad. bras. ciênc ; 73(1): 33-7, Mar. 2001. ilus, tab
Article in English | LILACS | ID: lil-281082
RESUMO
The essential oil from Piper solmsianum leaves and its major compound (sarisan) were tested to verify their influences upon mice behaviour. The essential oil was obtained by hydrodistillation in a modified Clevenger extractor and analysed by GC/ MS. This analysis revealed in the oil the presence of monoterpenes, sesquiterpenes and of arylpropanoids. The compound sarisan, a myristicin analogue, was isolated from the oil to perform the pharmacological tests. Emulsions of the oil and of sarisan (5.0 and 10.0 percent v/v) were used in the tests. Pentobarbital (30 mg/ kg s.c.) or diazepam (2.5 mg/ kg s.c.) were tested as standard drugs to verify depressant or anxiolytic effects, respectively. Both essential oil and sarisan showed to have exciting and depressant effects in the tested animals
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Full text: Available Index: LILACS (Americas) Main subject: Behavior, Animal / Plant Oils / Oils, Volatile Limits: Animals Language: English Journal: An. acad. bras. ciênc Journal subject: Science Year: 2001 Type: Article Affiliation country: Brazil Institution/Affiliation country: Jardim Botânico do Rio de Janeiro/BR / Universidade Federal do Rio de Janeiro/BR

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Full text: Available Index: LILACS (Americas) Main subject: Behavior, Animal / Plant Oils / Oils, Volatile Limits: Animals Language: English Journal: An. acad. bras. ciênc Journal subject: Science Year: 2001 Type: Article Affiliation country: Brazil Institution/Affiliation country: Jardim Botânico do Rio de Janeiro/BR / Universidade Federal do Rio de Janeiro/BR