Lack of antidiabetic effect of a Eugenia jambolana leaf decoction on rat streptozotocin diabetes
Braz. j. med. biol. res
;
34(3): 389-395, Mar. 2001. tab
Article
in English
| LILACS
| ID: lil-281621
RESUMO
Streptozotocin-diabetic rats were treated for 17 days with a decoction of Eugenia jambolana (Myrtaceae) leaves (15 percent, w/v) as a substitute for water. Body weight, food and fluid intake, urine volume, glycemia, urinary glucose and urea were evaluated every 5 days. The animals were sacrificed by decapitation and blood samples collected for the determination of glycemia, serum cholesterol, HDL-cholesterol, triglycerides and angiotensin-converting enzyme. The weight of adipose and muscle tissues was also determined. There were no statistically significant differences between treated and untreated rats for any of the biochemical or physiological parameters. We conclude that, at least in this experimental model, Eugenia jambolana leaf decoction has no antidiabetic activity
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Index:
LILACS (Americas)
Main subject:
Plants, Medicinal
/
Plant Extracts
/
Diabetes Mellitus, Experimental
/
Hypoglycemic Agents
Limits:
Animals
Language:
English
Journal:
Braz. j. med. biol. res
Journal subject:
Biology
/
Medicine
Year:
2001
Type:
Article
Affiliation country:
Brazil
Institution/Affiliation country:
Universidade Estadual Paulista/BR
/
Universidade de Säo Paulo/BR
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