Virus de la hepatitis C en un grupo de pacientes hematológicos y oncohematológicos / Hepatitis C virus in a group of hematological and oncohematological patients
Rev. méd. Chile
;
129(1): 18-22, ene. 2001. ilus, tab
Article
in Spanish
| LILACS
| ID: lil-282111
ABSTRACT
Background:
Little information is available in Chile about hepatitis C virus (HCV) in hematological and oncohematological patients.Aim:
To evaluate the prevalence of hepatitis C virus markers in a group of hematological and oncohematological pediatric patients seen at Valdivia Regional Hospital. Patients andmethods:
Antibodies against virus C, determined by ELISA and viral RNA, determined using RT-polymerase chain reaction, were measured in 54 blood samples from children with hematological diseases (34 with Acute Lymphoblastic Leukaemia, 4 with Hodgkin Diseases, 4 with Haemolytic Anemia, 5 with Sarcomas, 2 with Non-Hodgkin Lymphoma, 2 with Thrombocytopenic Purpura, 1 with an Ependimoma, one with a Wilms Tumor and 1 with a Von Willebrand Disease).Results:
All samples were negative for antibodies against hepatitis C virus. Viral RNA was found in four children, all with a diagnosis of acute lymphoblastic leukemia and who received chemotherapy and multiple transfusions.Conclusions:
The prevalence of Viral RNA for hepatitis C virus in oncohematological patients in our study is high and associated with the use of chemotherapy and multiple transfusions
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Hepacivirus
/
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Type of study:
Risk factors
Limits:
Adolescent
/
Child, preschool
/
Female
/
Humans
/
Infant
/
Male
Language:
Spanish
Journal:
Rev. méd. Chile
Journal subject:
Medicine
Year:
2001
Type:
Article
/
Project document
Similar
MEDLINE
...
LILACS
LIS