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Treatment of pemphigus vulgaris and pemphigus foliaceus: experience with 71 patients over a 20 year period
Fernandes, Nurimar C; Perez, Mauricio.
  • Fernandes, Nurimar C; Universidade Federal do Rio de Janeiro. Faculdade de Medicina. Departamento de Clínica Médica. BR
  • Perez, Mauricio; Universidade Federal do Rio de Janeiro. Faculdade de Medicina. Núcleo de Estudos em Saúde Coletiva. BR
Rev. Inst. Med. Trop. Säo Paulo ; 43(1): 33-36, Jan.-Feb. 2001. tab
Article in English | LILACS | ID: lil-285675
ABSTRACT
Forty one cases of pemphigus vulgaris and thirty cases of pemphigus foliaceus were investigated at Hospital Universitário Clementino Fraga Filho from 1978 to 1999. They were divided into two treatment groups one group received up to 100 mg of oral prednisone daily and the other group received >120 mg daily. The dose up to 100 mg provided good initial control of pemphigus vulgaris and pemphigus foliaceus and did not increase the mortality rate associated to disease. The dose >120 mg induced higher morbidity. These data allowed us to establish a regimen of oral prednisone (1-2 mg/kg/daily) with maximum of 120 mg daily in the treatment of pemphigus vulgaris and pemphigus foliaceus
Subject(s)
Full text: Available Index: LILACS (Americas) Main subject: Prednisone / Pemphigus Type of study: Observational study / Prognostic study / Risk factors Limits: Adolescent / Adult / Aged80 / Child / Female / Humans Language: English Journal: Rev. Inst. Med. Trop. Säo Paulo Journal subject: Tropical Medicine Year: 2001 Type: Article Affiliation country: Brazil Institution/Affiliation country: Universidade Federal do Rio de Janeiro/BR

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Full text: Available Index: LILACS (Americas) Main subject: Prednisone / Pemphigus Type of study: Observational study / Prognostic study / Risk factors Limits: Adolescent / Adult / Aged80 / Child / Female / Humans Language: English Journal: Rev. Inst. Med. Trop. Säo Paulo Journal subject: Tropical Medicine Year: 2001 Type: Article Affiliation country: Brazil Institution/Affiliation country: Universidade Federal do Rio de Janeiro/BR