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Cross-talk between neurons and glia: highlights on soluble factors
Gomes, F. C. A; Spohr, T. C. L. S; Martinez, R; Moura Neto, V.
  • Gomes, F. C. A; Universidade Federal do Rio de Janeiro. Departamento de Anatomia. Instituto de Ciências Biomédicas. Rio de Janeiro. BR
  • Spohr, T. C. L. S; Universidade Federal do Rio de Janeiro. Departamento de Anatomia. Instituto de Ciências Biomédicas. Rio de Janeiro. BR
  • Martinez, R; Universidade Federal do Rio de Janeiro. Departamento de Anatomia. Instituto de Ciências Biomédicas. Rio de Janeiro. BR
  • Moura Neto, V; Universidade Federal do Rio de Janeiro. Departamento de Anatomia. Instituto de Ciências Biomédicas. Rio de Janeiro. BR
Braz. j. med. biol. res ; 34(5): 611-620, May 2001. ilus
Article in English | LILACS | ID: lil-285874
ABSTRACT
The development of the nervous system is guided by a balanced action between intrinsic factors represented by the genetic program and epigenetic factors characterized by cell-cell interactions which neural cells might perform throughout nervous system morphogenesis. Highly relevant among them are neuron-glia interactions. Several soluble factors secreted by either glial or neuronal cells have been implicated in the mutual influence these cells exert on each other. In this review, we will focus our attention on recent advances in the understanding of the role of glial and neuronal trophic factors in nervous system development. We will argue that the functional architecture of the brain depends on an intimate neuron-glia partnership
Subject(s)
Full text: Available Index: LILACS (Americas) Main subject: Cell Communication / Neuroglia / Neurons Limits: Animals / Humans Language: English Journal: Braz. j. med. biol. res Journal subject: Biology / Medicine Year: 2001 Type: Article / Congress and conference / Project document Affiliation country: Brazil Institution/Affiliation country: Universidade Federal do Rio de Janeiro/BR

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Full text: Available Index: LILACS (Americas) Main subject: Cell Communication / Neuroglia / Neurons Limits: Animals / Humans Language: English Journal: Braz. j. med. biol. res Journal subject: Biology / Medicine Year: 2001 Type: Article / Congress and conference / Project document Affiliation country: Brazil Institution/Affiliation country: Universidade Federal do Rio de Janeiro/BR