Epidemiology of haemophilus influenzae invasive disease in Jamaica, 1990-1993
West Indian med. j
;
49(3): 200-4, Sept. 2000. tab, graf
Article
in English
| LILACS
| ID: lil-291972
ABSTRACT
Haemophilus influenzae (H influenzae) invasive disease was studied retrospectively over a four-year period in children admitted to the Bustamante Hospital for Children in Kingston, Jamaica. A total of 86cases were identified. The mean estimated annual incidence of H influenzae invasive disease in Kingston and St. Andrew was 39 per 100,000 children under 5 years of age. The majority (77percent) of cases were in the under 2-year age group. A distinct seasonal pattern was noted, with a significantly higher proportion of patients (57-73percent) presenting in the cooler months. Meningitis was the most common clinical diagnosis, accounting for 76percent of the cases. Poor outcome was demonstrated in 21.5percent of patients with meningitis. Sensitivity testing of H influenzae isolates revealed a resistance rate of 26percent for ampicillin and 7percent for chloramphenicol. The epidemiological findings in this study provide reasonable guidelines for empiric antibiotic therapy and also support the need to seriously consider vaccine prophylaxis in Jamaican children.
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Index:
LILACS (Americas)
Main subject:
Haemophilus influenzae
Type of study:
Diagnostic study
/
Practice guideline
/
Observational study
/
Prognostic study
/
Risk factors
/
Screening study
Limits:
Child, preschool
/
Female
/
Humans
/
Infant
Country/Region as subject:
English Caribbean
/
Jamaica
Language:
English
Journal:
West Indian med. j
Journal subject:
Medicine
Year:
2000
Type:
Article
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