Replacing oxamniquine by praziquantel against Schistosoma mansoni infection in a rural community from the sugar-cane zone of Northeast Brazil: an epidemiological follow-up
Mem. Inst. Oswaldo Cruz
;
96(suppl): 165-167, Sept. 2001. graf
Article
in English
| LILACS
| ID: lil-295888
ABSTRACT
A group of 52 villagers was followed-up for three years regarding Schistosoma mansoni infection. All villagers were periodically surveyed by the Kato-Katz method. In March 1997 and March 1998 the positives were treated with oxamniquine (15-20 mg/kg), and in March 1999, with praziquantel (60 mg/kg). All infection indices decreased substantially between March 1999 and March 2000 prevalence of infection (from 32.7 percent to 21.2 percent), prevalence of moderate/heavy infection (from 7.7 percent to 1.9 percent), intensity of infection (from 23.1 epg to 7.4 epg) and reinfection (from 35.7 percent to 14.3 percent). Negativation increased from 53.8 to 82.4. An optimistic prognostic is assumed in the short term for the introduction of praziquantel in the study area
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Oxamniquine
/
Praziquantel
/
Schistosomicides
/
Schistosomiasis mansoni
/
Anthelmintics
Type of study:
Observational study
/
Prevalence study
/
Prognostic study
/
Risk factors
Limits:
Animals
/
Humans
Country/Region as subject:
South America
/
Brazil
Language:
English
Journal:
Mem. Inst. Oswaldo Cruz
Journal subject:
Tropical Medicine
/
Parasitology
Year:
2001
Type:
Article
Affiliation country:
Brazil
Institution/Affiliation country:
Fiocruz/BR
Similar
MEDLINE
...
LILACS
LIS