Congenital Chagas disease of second generation in Santiago, Chile. Report of two cases
Rev. Inst. Med. Trop. Säo Paulo
;
43(4): 231-232, Aug. 2001.
Article
in English
| LILACS
| ID: lil-298689
ABSTRACT
Congenital Chagas disease (CChD) has been reported in different countries, mostly in Latin America. In 1987 a fatal case of CChD of second generation (CChDSG) was published. Within a period of six months - 1989-1990 - two cases of CChDSG were diagnosed and studied in the city of Santiago. Two premature newborns, sons of two sisters, with moderate liver and spleen enlargement, were found to have positive serology for Chagas disease and xenodiagnoses. The mothers, urban residents all their lives, without antecedents of triatomine bugs contact or blood transfusions, showed positive serology and xenodiagnoses. Their mother (grandmother of the infants), lived 20 years in a Northern rural Chagas disease endemic locality, in a triatomine infested house. Afterwards, she moved to Santiago, where she married and has resided up to now. Serology and xenodiagnoses were also positive. All the Trypanosoma cruzi infected individuals were successfully treated with nifurtimox
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Chagas Disease
Type of study:
Diagnostic study
Limits:
Child
/
Humans
/
Male
Country/Region as subject:
South America
/
Chile
Language:
English
Journal:
Rev. Inst. Med. Trop. Säo Paulo
Journal subject:
Tropical Medicine
Year:
2001
Type:
Article
Affiliation country:
Chile
Institution/Affiliation country:
Hospital Clínico de la Universidad de Chile/CL
/
Hospital San José/CL
/
Universidad de Chile/CL
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