Clinical and laboratory evaluation of measleslike rash in children and young adults
Braz. j. microbiol
;
31(4): 281-285, oct.-dec. 2000. tab
Article
in English, Portuguese
| LILACS
| ID: lil-299825
RESUMO
A clinical and laboratory evaluation of 11 childrens and young adults with measleslike rash was done during the measles outbreak in the Greater São Paulo Metropolitan area at the end of 1996 and spread over the country during 1997. Measles was laboratory confirmed in 07 patients by specific IgM detection in acute serum specimens using an IgM-capture EIA, by specific IgG seroconversion in serum pairs, and by reverse transcription PCR and virus isolation in peripheral blood lymphocytes. Clinical presentations were not always classic; one of the 07 cases had received measles vaccine and corresponded to modified clinical case of measles. The 4 remaining cases were negative for measles and were diagnosed as exanthem subitum (2 cases), scarlet fever and Kawasaki disease. The present study reinforces the view that clinical features alone are not sufficient for establishing an accurate diagnosis in the post-vaccine era, and a surveillance system based on sensitive laboratory results is needed so that it can confirm IgM-negative measles cases.
Full text:
Available
Index:
LILACS (Americas)
Main subject:
In Vitro Techniques
/
Polymerase Chain Reaction
/
Measles
Type of study:
Diagnostic study
Limits:
Adolescent
/
Adult
/
Humans
Language:
English
/
Portuguese
Journal:
Braz. j. microbiol
Journal subject:
Microbiology
Year:
2000
Type:
Article
Affiliation country:
Brazil
Institution/Affiliation country:
Instituto Adolfo Lutz/BR
/
Instituto Butantan/BR
/
Universidade Federal do Paraná/BR
/
Universidade de São Paulo/BR
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