Breast cancer with choriocarcinomatous and neuroendocrine features
São Paulo med. j
;
119(4): 154-155, July 2001. ilus
Article
in English
| LILACS
| ID: lil-302323
RESUMO
CONTEXT: Breast cancer may express the presence of b-human chorionic gonadotrophin in 12 percent to 18 percent of cases, using immunohistochemical reactions. Usually the tumors will show positivity in a few scattered cells. Breast cancer with choriocarcinomatous features, as reported by Saigo and Rosen, is a distinct variant of breast cancer. We report a case of breast cancer with choriocarcinomatous and neuroendocrine features. OBJECTIVE: This is a case report of an invasive ductal carcinoma of the breast with choriocarcinomatous and neuroendocrine features. DESIGN: Case Report. CASE REPORT: A 50-year-old Brazilian woman underwent surgery for a lump in the right breast, which had been first noticed about 3 months earlier. The surgery consisted of quadrantectomy followed by right mastectomy with ipsilateral axillary lymph node dissection. The specimen from the quadrantectomy revealed a 7 x 6.5 x 4.5 cm tumor. Histology of the lesion showed the presence of an invasive ductal carcinoma with areas of giant cells and intense atypia. The immunohistochemistry was positive in the pleomorphic areas for human chorionic gonadotrophin, while the less pleomorphic areas showed positivity for synaptophysin and chromogranin
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Breast Neoplasms
/
Choriocarcinoma
/
Carcinoma, Ductal, Breast
Limits:
Female
/
Humans
Language:
English
Journal:
São Paulo med. j
Journal subject:
Cirurgia Geral
/
Cincia
/
Ginecologia
/
Medicine
/
Medicina Interna
/
Obstetr¡cia
/
Pediatria
/
Sa£de Mental
/
Sa£de P£blica
Year:
2001
Type:
Article
Affiliation country:
Brazil
Institution/Affiliation country:
Universidade Federal de Säo Paulo/BR
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